PMDI, WANNATE® 2208
WANNATE® 2208 is a dark brown liquid at room temperature, composed of diphenylmethane diisocyanate (MDI) and higher-functionality isocyanate oligomers.
Product Overview
Application Benefits
Physicochemical Properties
| Parameter | Specification | Test Standard |
|---|---|---|
| Appearance | Dark brown liquid | Visual inspection |
| Viscosity (25°C) | 150–250 mPa·s | GB 12009.3 |
| -NCO Content | 30.2–32.0% | GB 12009.4 |
| Density (25°C) | 1.22–1.25 g/cm³ | GB 4472 |
| Acidity (as HCl) | ≤0.05% | GB 12009.5 |
| Hydrolyzable Chloride | ≤0.2% | GB 12009.2 |
Packaging Specifications
210L iron drum, 250 kg/drum，In bulk
Storage & Handling
Chemical Safety Data Sheet
Hazards Identification
Emergency Overview: Liquid, flammable, harmful if inhaled, irritating to eyes, may cause respiratory irritation, irritating to skin, may cause sensitization by inhalation, may cause sensitization by skin contact, risk of cumulative effects, limited evidence of carcinogenicity. Long-term exposure by inhalation, skin contact and ingestion may cause serious health hazards.
GHS Hazard Classifications:
Serious eye damage/eye irritation Category 2A
Respiratory sensitizer Category 1
Specific target organ toxicity – repeated exposure Category 2
Acute toxicity – inhalation Category 4
Specific target organ toxicity – single exposure Category 3
Skin corrosion/irritation Category 2
Skin sensitizer Category 1
Carcinogen Category 2
Label Elements:
Pictogram: (As per GHS standard)
Signal Word: Danger
Hazard Statements:
H319: Causes serious eye irritation.
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H373: May cause damage to organs through prolonged or repeated exposure.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
H315: Causes skin irritation.
H317: May cause an allergic skin reaction.
H351: Suspected of causing cancer.
Precautionary Statements:
Prevention:
P201: Obtain special instructions before use.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P284: Wear respiratory protection in insufficient ventilation.
P272: Contaminated work clothing should not be allowed out of the workplace.
Response:
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P308+P313: IF exposed or concerned: Get medical advice/attention.
P310: Immediately call a POISON CENTER or doctor/physician.
P342+P311: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P333+P313: If skin irritation or rash occurs: Get medical advice/attention.
P337+P313: If eye irritation persists: Get medical advice/attention.
P362+P364: Take off contaminated clothing and wash before reuse.
Storage:
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
Disposal:
P501: Dispose of contents/container to national and local regulations.
Physical and Chemical Hazards: Solid, flammable. Vapors/gases are heavier than air. Fire produces toxic fumes. Reacts with water.
Health Hazards:
Inhalation: This substance may cause respiratory irritation in some individuals. The body’s response to this irritation may cause further lung damage. Inhalation of aerosols (mist, fume) of this substance during normal processing may be harmful.
Vapors/mists may severely irritate the respiratory tract and lungs; consequences may be severe enough to cause bronchitis and pulmonary edema. Isocyanate exposure may cause neurological symptoms such as headache, insomnia, euphoria, ataxia, anxiety neurosis, hypotension and paranoia. Gastrointestinal disorders manifest as nausea and vomiting.
Pulmonary allergy may lead to varying degrees of asthma symptoms, from slight shortness of breath to severe allergic reactions; this may occur after a single intense exposure or without warning hours after exposure. Sensitive individuals may react to very low doses and must not work in environments exposed to this substance. Continued exposure may result in long-term respiratory organ damage.
Inhalation hazards increase with rising temperature.
Ingestion: If swallowed, seek medical advice immediately.
Skin Contact: Skin contact may cause inflammation or allergic reactions in some individuals.
Eyes: Direct eye contact may cause temporary discomfort, lacrimation or conjunctival redness. If splashed in eyes, seek medical advice immediately.
Chronic: Individuals with a history of asthma, other respiratory problems or allergies must be prohibited from engaging in any operations involving isocyanates.
Environmental Hazards: See Section 12.
Composition/Information on Ingredients
| Component | Concentration or Concentration Range % | CAS No. |
| Polymethylene polyphenyl isocyanate | 100 | 9016-87-9 |
Note: Diphenylmethane diisocyanate (30%–50%) and polymethylene polyphenyl polyisocyanate (50%–70%) are both part of polymethylene polyphenyl isocyanate (9016-87-9).
First-Aid Measures
First Aid:
Skin Contact: Immediately remove all contaminated clothing, including shoes and socks. Flush skin and hair with running water (soap if available); seek medical advice if irritation occurs.
Special Advice for Doctors:
For subchronic and chronic exposure to isocyanates:
This substance is a pulmonary sensitizer; bronchospasm may occur even in patients with no history of respiratory allergy.
Clinical symptoms after exposure include irritation of respiratory and gastrointestinal mucosa.
Conjunctival irritation, dermatitis (redness, blisters with pain) and gastrointestinal disorders occur shortly after exposure.
Pulmonary symptoms include cough, burning pain, substernal pain and dyspnea.
There is no effective treatment for sensitized workers.
Fire-Fighting Measures
Fire Fighting Procedures and Precautions:
Inform the fire brigade and advise the location and hazard characteristics of the accident. Wear full protective clothing and breathing apparatus. Take effective measures to prevent spillage from entering sewers or water bodies. Use water spray to control fire and cool adjacent areas. Do not direct water spray directly into the liquid pool.
Accidental Release Measures
Methods and Materials for Containment and Cleaning Up:
Small Spillage: Dispose of waste regularly; abnormal spillage should be cleaned up immediately. Avoid contact with skin and eyes. Wear protective clothing, gloves and safety goggles.
Handling and Storage
Handling Precautions:
Safe Handling: Wear protective clothing when there is a risk of contact. Use in a well-ventilated area. Prevent accumulation in low-lying areas. Do not enter confined spaces without air testing. Prohibit contact with human body, food or food containers. Avoid contact with incompatible materials. Do not eat, drink or smoke during handling. Keep containers safely sealed when not in use. Protect containers from physical damage. Wash hands with soap and water after handling. Work clothing should be laundered separately. Contaminated clothing must be laundered before reuse. Regularly monitor hazardous substance concentrations in the workplace and comply with relevant standards to ensure workplace safety.
Storage Precautions:
Storage Incompatibilities: Avoid reaction with water, alcohols, strong bases, metal compounds or detergent solutions. The substance reacts with water to produce large amounts of foam, carbon dioxide and heat. Foaming in confined spaces may cause pressure buildup. Isocyanates may corrode and embrittle certain plastics and rubbers.
Exposure Controls/Personal Protection
Exposure Limits:
| Source | Substance Name | TWA | STEL | Remarks |
| China Occupational Exposure Limits for Hazardous Agents in the Workplace | Diphenylmethane diisocyanate | 0.05 mg/m³ | 0.1 mg/m³ | – |
Biological Limit Values: Not established.
Monitoring Method: Not established.
Engineering Controls: Basic types of engineering controls include:
Process control by modifying work activities or processes to reduce risks. Enclose and/or isolate emission sources. Ventilation system design must comply with specific processes and chemicals or pollutants used. Ventilation systems shall be designed to prevent accumulation or recirculation of particulates in the workplace. Respiratory protection should be considered if airborne concentrations may reach harmful levels under local ventilation.
Physical and Chemical Properties
Appearance: Dark brown liquid
Odor: No data available
pH Value (as specified): Not applicable
Melting/Freezing Point (℃): 5
Boiling Point, Initial Boiling Point and Boiling Range (℃): >300
Density: No data available
Relative Vapor Density (air=1): 8.5
Relative Density (water=1): 1.24
Critical Pressure (MPa): No data available
Saturated Vapor Pressure: 0.00031 Pa
Flash Point (℃): >230
Critical Temperature (℃): No data available
Decomposition Temperature (℃): No data available
n-Octanol/Water Partition Coefficient: No data available
Solubility: Reacts with water.
Autoignition Temperature (℃): >600
Lower Explosion Limit [%(V/V)]: No data available
Flammability: No data available
Upper Explosion Limit [%(V/V)]: No data available
Viscosity (cSt): No data available
Stability and Reactivity
Incompatible Materials: See Section 7.
Conditions to Avoid: See Section 7.
Hazardous Reactions: See Section 7.
Hazardous Decomposition Products: See Section 5.
Toxicological Information
Acute Toxicity:
Polymethylene polyphenyl isocyanate: Inhalation (rat) LC50: 367.95–558.98 mg/m³ air/4h; Oral (rat) LD50: >2000 mg/kg
Diphenylmethane-4,4'-diisocyanate: Dermal (rabbit) LD50: >6200 mg/kg; Inhalation (rat) LC50: 367.95–558.98 mg/m³ air/4h
Chronic Toxicity: Isocyanate vapors irritate the respiratory tract, causing inflammation with wheezing, dyspnea, severe distress, unconsciousness and pulmonary edema. Neurological symptoms may include headache, sleep disorders, euphoria, ataxia, anxiety, depression and paranoia. Gastrointestinal symptoms include nausea and vomiting. Dyspnea may occur suddenly after a period of tolerance or skin contact. Allergic dermatitis may occur, presenting as rash, itching, urticaria and swelling of extremities. Allergic individuals react to very small amounts of the substance and must not be exposed to it.
This substance may cause moderate eye irritation leading to inflammation. Repeated or prolonged contact may cause conjunctivitis. This substance is classified by IARC as Category 3: not classifiable as to carcinogenicity to humans. Evidence of carcinogenicity may be insufficient or limited to animal studies.
Ecological Information
| Substance Name | Endpoint | Test Duration | Species | Value |
| Polymethylene polyphenyl isocyanate | LC50 | 4 days | Fish (short-term toxicity) | 1 g/L |
| EC50 | 72 h | Algae | 1.64 g/L | |
| Diphenylmethane-4,4'-diisocyanate | LC50 | 4 days | Fish (short-term toxicity) | >0.500 mg/L |
| EC50 | 24 h | Freshwater aquatic invertebrates | 129.7–1000 mg/L | |
| EC50 | 72 h | Algae | 1.64 g/L |
Persistence and Degradability:
| Component | Persistence: Water (25°C) | Persistence: Air |
| Diphenylmethane-4,4'-diisocyanate | Low (half-life = 20 hours) | Low (half-life = 1 day) |
Bioaccumulation Potential:
| Component | Bioaccumulation (Aquatic Environment/Sediment) |
| Diphenylmethane-4,4'-diisocyanate | Low (BCF = 200) |
Mobility in Soil:
| Component | Bioaccumulation (Aquatic Environment/Sediment) |
| Diphenylmethane-4,4'-diisocyanate | Low (KOC = 376200) |
Disposal Considerations
Transport Information
UN Transport: Not regulated as a dangerous good for road, air, rail or sea transport.
Packing Group: Not regulated as a dangerous good for road, air, rail or sea transport.
Packing Label: Not regulated as a dangerous good for road, air, rail or sea transport.
Packaging Methods: See Section 7.
Marine Pollutant (Yes/No): No
Transport Precautions: Check that packaging containers are intact and sealed before transport. Ensure containers do not leak, collapse, fall or be damaged during transport.
Regulatory Information
- Inventory of Existing Chemical Substances in China
- IARC Monographs
- Catalogue of Hazardous Chemicals
- China Occupational Exposure Limits for Hazardous Agents in the Workplace
- Inventory of Existing Chemical Substances in China
- IARC Monographs
Australia – AICS: Yes
Canada – DSL: Yes; NDSL: No
Korea – KECI: Yes
China – IECSC: Yes
EU – EINECS/ELINCS/NLP: Yes
Japan – ENCS: Yes
New Zealand – NZIoC: Yes
Philippines – PICCS: Yes
USA – TSCA: Yes
Taiwan, China – TCSI: Yes
Mexico – INSQ: Yes
Vietnam – NCI: Yes
Russia – FBEPH: Yes
Other Information
Abbreviations:
PC-TWA: Permissible Concentration–Time Weighted Average
PC-STEL: Permissible Concentration–Short Term Exposure Limit
IARC: International Agency for Research on Cancer
ACGIH: American Conference of Governmental Industrial Hygienists
STEL: Short Term Exposure Limit
NOAEL: No Observed Adverse Effect Level
BCF: BioConcentration Factor
Disclaimer
| Weight | 250 kg |
|---|
